Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Aoshima, M.; Ishii, M.; Igarashi, Y.
    A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6 (2004), Mol. Microbiol., 51, 791-798.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.4.1.7 expression in Escherichia coli Hydrogenobacter thermophilus

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.4.1.7 Avidin
-
 Hydrogenobacter thermophilus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.4.1.7 Mg2+ required Hydrogenobacter thermophilus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.7 49000
-
 x * 72000 + x * 49000, likely subunit structure alpha8beta8, SDS-PAGE Hydrogenobacter thermophilus
6.4.1.7 72000
-
 x * 72000 + x * 49000, likely subunit structure alpha8beta8, SDS-PAGE Hydrogenobacter thermophilus
6.4.1.7 998000
-
 gel filtration Hydrogenobacter thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.7 ATP + 2-oxoglutarate + HCO3- Hydrogenobacter thermophilus
-
 ADP + phosphate + oxalosuccinate
-
 ?
6.4.1.7 ATP + 2-oxoglutarate + HCO3- Hydrogenobacter thermophilus TK-6 / IAM 12695
-
 ADP + phosphate + oxalosuccinate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.7 Hydrogenobacter thermophilus
-
 TK-6
-
6.4.1.7 Hydrogenobacter thermophilus TK-6 / IAM 12695
-
 TK-6
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.4.1.7
-
 Hydrogenobacter thermophilus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.7 ATP + 2-oxoglutarate + HCO3-
-
 Hydrogenobacter thermophilus ADP + phosphate + oxalosuccinate
-
 ?
6.4.1.7 ATP + 2-oxoglutarate + HCO3-
-
 Hydrogenobacter thermophilus TK-6 / IAM 12695 ADP + phosphate + oxalosuccinate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.7 ? x * 72000 + x * 49000, likely subunit structure alpha8beta8, SDS-PAGE Hydrogenobacter thermophilus

Synonyms

EC Number Synonyms Comment Organism
6.4.1.7 carboxylating factor for ICDH incorrect Hydrogenobacter thermophilus
6.4.1.7 CFI
-
 Hydrogenobacter thermophilus
6.4.1.7 OGC
-
 Hydrogenobacter thermophilus
6.4.1.7 oxalosuccinate synthetase
-
 Hydrogenobacter thermophilus

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.7 biotin enzyme contains biotin Hydrogenobacter thermophilus