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Literature summary extracted from
- Purification of PA700, the 19S regulatory complex of the 26S proteasome (2005), Methods Enzymol., 398, 295-306.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.6.1.5 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | blood | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.5 | ATP + H2O + polypeptide | the 26S proteasome is a 2400000 Da protease complex that selectively degrades proteins modified by polyubiquitin chains. The 26S proteasome is composed of two 700000 Da multisubunit complexes: the 20S proteasome, which serves as the proteolytic core of the complex, and PA700, an ATPase regulatory complex responsible for the binding, modification, and delivery of substrates to the proteolytic chamber | Bos taurus | ADP + phosphate + unfolded polypeptide | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.6.1.5 | More | the 26S proteasome is a 2400000 Da protease complex that selectively degrades proteins modified by polyubiquitin chains. The 26S proteasome is composed of two 700000 Da multisubunit complexes: the 20S proteasome, which serves as the proteolytic core of the complex, and PA700, an ATPase regulatory complex responsible for the binding, modification, and delivery of substrates to the proteolytic chamber | Bos taurus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.1.5 | P700 | the 26S proteasome is a 2400000 Da protease complex that selectively degrades proteins modified by polyubiquitin chains. The 26S proteasome is composed of two 700000 Da multisubunit complexes: the 20S proteasome, which serves as the proteolytic core of the complex, and PA700, an ATPase regulatory complex responsible for the binding, modification, and delivery of substrates to the proteolytic chamber | Bos taurus |
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