Literature summary extracted from

Pecheniuk, N.M.; Deguchi, H.; Griffin, J.H.
Cholesterol enhances phospholipid-dependent activated protein C anticoagulant activity (2005), J. Thromb. Haemost., 3, 340-345.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.4.21.69	cholesterol	in phosphatidylcholine/phosphatidylserine vesicles, cholesterol enhances Factor Va inactivation and the rate of cleavage by enzyme both at R506 and R306	Homo sapiens

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.69	Homo sapiens	-	commercial preparation from Enzyme Research Laboratories, South Bend, USA	-

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Release 2023.1 (January 2023)