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Literature summary extracted from

  • Lacey, M.; Bohday, J.; Fonseka, S.M.; Ullah, A.I.; Whitehead, S.A.
    Dose-response effects of phytoestrogens on the activity and expression of 3beta-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells (2005), J. Steroid Biochem. Mol. Biol., 96, 279-286.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.145 Biochanin A
-
 Homo sapiens
1.1.1.145 additional information no inhibition by quercetin, apigenin, genistein, daidzein, enterodiol, and enterolactone Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.145 5-pregnen-3beta-ol-2-one + NAD+ Homo sapiens
-
 progesterone + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.145 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.145 corpus luteum primary culture Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.145 5-pregnen-3beta-ol-2-one + NAD+
-
 Homo sapiens progesterone + NADH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.145 3beta-HSD
-
 Homo sapiens
1.1.1.145 3beta-hydroxysteroid dehydrogenase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.145 NAD+
-
 Homo sapiens