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Literature summary extracted from

  • Dibas, A.; Prasanna, G.; Yorio, T.
    Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line (2005), J. Ocul. Pharmacol. Ther., 21, 196-204.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.71 1,10-phenanthroline 1 mM, inhibition of ECE-1 activity Homo sapiens
3.4.24.71 additional information acidification to pH 6.4 inhibits plasma membrane ECE activity Homo sapiens
3.4.24.71 phosphoramidon 0.1 M, 35% inhibition of ECE-1 activity Homo sapiens
3.4.24.71 thiorphan 1 mM, inhibition of ECE-1 activity Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.71 plasma membrane
-
Homo sapiens 5886
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.71 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.71 retinal pigment epithelium cell line
-
Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.24.71 ECE-1
-
Homo sapiens
3.4.24.71 endothelin-converting enzyme-1
-
Homo sapiens