EC Number | Application | Comment | Organism |
---|---|---|---|
2.7.8.27 | medicine | adenovirus-mediated SMS1 overexpression increases lipoprotein atherogenic potential. Such an effect may contribute to the increased plasma sphingomyelin levels observed in animal models of atherosclerosis and in human patients with coronary artery disease | Mus musculus |
2.7.8.27 | medicine | adenovirus-mediated SMS2 overexpression increases lipoprotein atherogenic potential. Such an effect may contribute to the increased plasma sphingomyelin levels observed in animal models of atherosclerosis and in human patients with coronary artery disease | Mus musculus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.8.27 | adenovirus approach to overexpress SMS1 in mice to investigate the relationship between sphingomyelin synthase and sphingomyelin metabolism | Mus musculus |
2.7.8.27 | adenovirus approach to overexpress SMS2 in mice to investigate the relationship between sphingomyelin synthase and sphingomyelin metabolism | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.8.27 | Mus musculus | Q8VCQ6 | - |
- |
2.7.8.27 | Mus musculus | Q9D4B1 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.8.27 | liver | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.8.27 | 6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine + phosphatidylcholine | - |
Mus musculus | N-hexanoyl-4-nitrobenz-2-oxa-1,3-diazole-sphingomyelin + 1,2-diacylglycerol | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.8.27 | SMS1 | - |
Mus musculus |
2.7.8.27 | SMS2 | - |
Mus musculus |
2.7.8.27 | sphingomyelin synthases 1 | - |
Mus musculus |
2.7.8.27 | sphingomyelin synthases 2 | - |
Mus musculus |