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Literature summary extracted from

  • Goshima, G.; Nedelec, F.; Vale, R.D.
    Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins (2005), J. Cell Biol., 171, 229-240.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.6.1.4 microtubule growing tip of centrosomal microtubule Drosophila melanogaster 5874
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n Drosophila melanogaster dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.2 Drosophila melanogaster
-
-
-
5.6.1.4 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.2 SCHNEIDER-2 cell
-
 Drosophila melanogaster
-
5.6.1.4 SCHNEIDER-2 cell
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n
-
 Drosophila melanogaster ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes Drosophila melanogaster ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
 Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Ncd is primarily responsible for focusing kinetochore microtubule bundles (K fibers) Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.2 dynein
-
 Drosophila melanogaster
5.6.1.4 ncd
-
 Drosophila melanogaster