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Literature summary extracted from

  • Weskamp, G.; Schloendorff, J.; Lum, L.; Becherer, J.D.; Kim, T.; Saftig, P.; Hartmann, D.; Murphy, G.; Blobel, C.P.
    Evidence for a critical role of the tumor necrosis factor a convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR) (2004), J. Biol. Chem., 279, 4241-4249.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.86 p75 neurotrophin receptor + H2O Cricetulus griseus critical role of TACE in ectodomain shedding of the p75 neurotrophin receptor ?
-
 ?
3.4.24.86 p75 neurotrophin receptor + H2O Mus musculus critical role of TACE in ectodomain shedding of the p75 neurotrophin receptor ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.86 Cricetulus griseus
-
-
-
3.4.24.86 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.86 CHO cell
-
 Cricetulus griseus
-
3.4.24.86 fibroblast
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.86 p75 neurotrophin receptor + H2O
-
 Cricetulus griseus ?
-
 ?
3.4.24.86 p75 neurotrophin receptor + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 p75 neurotrophin receptor + H2O critical role of TACE in ectodomain shedding of the p75 neurotrophin receptor Cricetulus griseus ?
-
 ?
3.4.24.86 p75 neurotrophin receptor + H2O critical role of TACE in ectodomain shedding of the p75 neurotrophin receptor Mus musculus ?
-
 ?