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Literature summary extracted from
- ire-1-dependent transcriptional up-regulation of a lumenal uridine diphosphatase from Caenorhabditis elegans (2004), J. Biol. Chem., 279, 27390-27398.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.6 | additional information | no enzymatic activity in the presence of EDTA | Caenorhabditis elegans |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.6.1.6 | expressed in Saccharomyces cerevisiae gda1-null mutant | Caenorhabditis elegans |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.6 | 0.18 | - |
UDP | at pH 8.0 in the presence of 10 mM Ca2+ | Caenorhabditis elegans |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.6.1.6 | membrane | - |
Caenorhabditis elegans | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.6 | Ca2+ | 10 mM, stimulation | Caenorhabditis elegans | |
| 3.6.1.6 | Mg2+ | 10 mM, stimulation | Caenorhabditis elegans | |
| 3.6.1.6 | Mn2+ | 10 mM, stimulation | Caenorhabditis elegans | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.6 | Caenorhabditis elegans | - |
strains N2 and RE666 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.6 | GDP + H2O | - |
Caenorhabditis elegans | GMP + phosphate | - |
? | |
| 3.6.1.6 | UDP + H2O | - |
Caenorhabditis elegans | UMP + phosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.6.1.6 | lumenal ecto-nucleoside di-phosphohydrolase | - |
Caenorhabditis elegans |
| 3.6.1.6 | lumenal uridine diphosphatase | - |
Caenorhabditis elegans |
| 3.6.1.6 | UDA-1 | - |
Caenorhabditis elegans |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.6 | 7.5 | - |
with GDP as substrate | Caenorhabditis elegans |
| 3.6.1.6 | 8 | - |
with UDP as substrate | Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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