BRENDA - Enzyme Database

Regulation and physiologic significance of the agmatine deiminase system of Streptococcus mutans UA159

Griswold, A.R.; Jameson-Lee, M.; Burne, R.A.; J. Bacteriol. 188, 834-841 (2006)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.5.3.12
expression in Escherichia coli DH10B
Streptococcus mutans
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.5.3.12
agmatine
AgDS-deficient strain is unable to grow in the presence of 20 mM agmatine, suggesting that AgDS converts a growth-inhibitory substance into products that can enhance acid tolerance
Streptococcus mutans
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.5.3.12
Streptococcus mutans
-
-
-
3.5.3.12
Streptococcus mutans UA159
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.3.12
agmatine + H2O
agmatine deiminase system (AgDS)
669131
Streptococcus mutans
N-carbamoylputrescine + NH3
-
-
-
?
3.5.3.12
agmatine + H2O
agmatine deiminase system (AgDS)
669131
Streptococcus mutans UA159
N-carbamoylputrescine + NH3
-
-
-
?
Temperature Range [C]
EC Number
Temperature Minimum [C]
Temperature Maximum [C]
Commentary
Organism
3.5.3.12
37
40
AgD activity 4fold higher in Streptococcus mutans grown at 42C than at 37C, stress response pathway of this organism
Streptococcus mutans
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
3.5.3.12
5
7
AgD induction clearly enhanced at low pH values, aguA ca. 3.7fold higher in cells grown at pH 5 than that grown at pH 7, stress response pathway of this organism
Streptococcus mutans
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.5.3.12
expression in Escherichia coli DH10B
Streptococcus mutans
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.5.3.12
agmatine
AgDS-deficient strain is unable to grow in the presence of 20 mM agmatine, suggesting that AgDS converts a growth-inhibitory substance into products that can enhance acid tolerance
Streptococcus mutans
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.3.12
agmatine + H2O
agmatine deiminase system (AgDS)
669131
Streptococcus mutans
N-carbamoylputrescine + NH3
-
-
-
?
3.5.3.12
agmatine + H2O
agmatine deiminase system (AgDS)
669131
Streptococcus mutans UA159
N-carbamoylputrescine + NH3
-
-
-
?
Temperature Range [C] (protein specific)
EC Number
Temperature Minimum [C]
Temperature Maximum [C]
Commentary
Organism
3.5.3.12
37
40
AgD activity 4fold higher in Streptococcus mutans grown at 42C than at 37C, stress response pathway of this organism
Streptococcus mutans
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
3.5.3.12
5
7
AgD induction clearly enhanced at low pH values, aguA ca. 3.7fold higher in cells grown at pH 5 than that grown at pH 7, stress response pathway of this organism
Streptococcus mutans