EC Number | Cloned (Comment) | Organism |
---|---|---|
2.5.1.86 | - |
Mycolicibacterium smegmatis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.68 | cytosol | major activity | Mycolicibacterium smegmatis | 5829 | - |
2.5.1.68 | cytosol | major activity | Mycobacterium tuberculosis | 5829 | - |
2.5.1.68 | membrane | minor activity | Mycolicibacterium smegmatis | 16020 | - |
2.5.1.68 | membrane | minor activity | Mycobacterium tuberculosis | 16020 | - |
2.5.1.86 | membrane | associated | Mycolicibacterium smegmatis | 16020 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.68 | Mg2+ | activates | Mycolicibacterium smegmatis | |
2.5.1.68 | Mg2+ | activates | Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | Mycolicibacterium smegmatis | step in polyprenylphosphate biosynthesis, overview | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | Mycobacterium tuberculosis | step in polyprenylphosphate biosynthesis, overview | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | Mycobacterium tuberculosis H37Rv | step in polyprenylphosphate biosynthesis, overview | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.86 | (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate | Mycolicibacterium smegmatis | the enzyme is involved in decaprenyl phosphate synthesis, that is important in the rate of bacterial growth and the synthesis of cell wall components | 7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.68 | Mycobacterium tuberculosis | - |
- |
- |
2.5.1.68 | Mycobacterium tuberculosis H37Rv | - |
- |
- |
2.5.1.68 | Mycolicibacterium smegmatis | - |
- |
- |
2.5.1.86 | Mycolicibacterium smegmatis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | stereospecific reaction | Mycolicibacterium smegmatis | (2Z,6E)-farnesyl diphosphate + diphosphate | i.e. omega,E,Z-farnesyl diphosphate | ? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | stereospecific reaction | Mycobacterium tuberculosis | (2Z,6E)-farnesyl diphosphate + diphosphate | i.e. omega,E,Z-farnesyl diphosphate | ? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | step in polyprenylphosphate biosynthesis, overview | Mycolicibacterium smegmatis | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | step in polyprenylphosphate biosynthesis, overview | Mycobacterium tuberculosis | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | stereospecific reaction | Mycobacterium tuberculosis H37Rv | (2Z,6E)-farnesyl diphosphate + diphosphate | i.e. omega,E,Z-farnesyl diphosphate | ? | |
2.5.1.68 | geranyl diphosphate + isopentenyl diphosphate | step in polyprenylphosphate biosynthesis, overview | Mycobacterium tuberculosis H37Rv | (2Z,6E)-farnesyl diphosphate + diphosphate | - |
? | |
2.5.1.86 | (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate | - |
Mycolicibacterium smegmatis | 7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate | - |
? | |
2.5.1.86 | (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate | the enzyme is involved in decaprenyl phosphate synthesis, that is important in the rate of bacterial growth and the synthesis of cell wall components | Mycolicibacterium smegmatis | 7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.5.1.68 | 37 | - |
assay at | Mycolicibacterium smegmatis |
2.5.1.68 | 37 | - |
assay at | Mycobacterium tuberculosis |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.5.1.68 | 7.9 | - |
assay at | Mycolicibacterium smegmatis |
2.5.1.68 | 7.9 | - |
assay at | Mycobacterium tuberculosis |