Literature summary extracted from

Wakino, S.; Hayashi, K.; Tatematsu, S.; Hasegawa, K.; Takamatsu, I.; Kanda, T.; Homma, K.; Yoshioka, K.; Sugano, N.; Saruta, T.
Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats (2005), Hypertens. Res., 28, 255-262.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.5.3.18	additional information	mRNA expression levels of DDAH-I are not changed in pioglitazone-treated rats	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.3.18	Rattus norvegicus	-	Wister-Kyoto rat and spontaneously hyptertensive rat	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.5.3.18	kidney	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.3.18	NG,NG-dimethyl-L-arginine + H2O	-	Rattus norvegicus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.5.3.18	DDAH-I	-	Rattus norvegicus
3.5.3.18	dimethylarginine dimethylaminohydrolase	-	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)