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Literature summary extracted from
- Fibrolase (2004), Handbook of Proteolytic Enzymes (Barrett,A. J. ;Rawlings,N. D. ,Woessner), 1, 640-643.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.72 | 1,10-phenanthroline | complete and rapid inhibition | Agkistrodon contortrix |  |
| 3.4.24.72 | alpha2-Macroglobulin | - |
Agkistrodon contortrix | |
| 3.4.24.72 | EDTA | complete and rapid inhibition | Agkistrodon contortrix | |
| 3.4.24.72 | additional information | not inhibited by any serine protease inhibitor | Agkistrodon contortrix | |
| 3.4.24.72 | Tetraethylenepentamine | complete and rapid inhibition | Agkistrodon contortrix | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.72 | 23000 | - |
calculation from amino acid sequence | Agkistrodon contortrix |
| 3.4.24.72 | 25000 | - |
SDS-PAGE | Agkistrodon contortrix |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.72 | Agkistrodon contortrix | - |
subspecies Agkistrodon contortrix contortrix, southern copperhead snake | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.72 | hydroxyapatite chromatography, cation exchange chromatography | Agkistrodon contortrix |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.72 | venom | - |
Agkistrodon contortrix | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.72 | Abz-His-Thr-Glu-Lys-Leu-Val-Thr-Ser-2,4-dinitrophenyl + H2O | - |
Agkistrodon contortrix | Abz-His-Thr-Glu-Lys + Leu-Val-Thr-Ser-2,4-dinitrophenyl | - |
? | |
| 3.4.24.72 | alpha2-macroglobulin + H2O | - |
Agkistrodon contortrix | fragments of alpha2-macroglobulin | - |
? | |
| 3.4.24.72 | azocasein + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
| 3.4.24.72 | Fibrin + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
| 3.4.24.72 | fibrinogen alpha chain + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.72 | fibrinolytic protease | - |
Agkistrodon contortrix |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.72 | 7.4 | - |
- |
Agkistrodon contortrix |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.4.24.72 | Agkistrodon contortrix | - |
- |
6.8 |
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