Literature summary extracted from

Karlstroem, M.; Steen, I.H.; Madern, D.; Fedoey, A.E.; Birkeland, N.K.; Ladenstein, R.
The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima (2006), FEBS J., 273, 2851-2868.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
1.1.1.42	dimeric apoform	Thermotoga maritima

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.1.1.42	D389N	reduction in apparent melting temperature by 21.8°C compared to wild-type	Thermotoga maritima
1.1.1.42	F205M	reduction in apparent melting temperature by 3.5°C compared to wild-type	Thermotoga maritima
1.1.1.42	R186M	no change in apparent melting temperature compared to wild-type	Thermotoga maritima

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.42	Thermotoga maritima	Q9X0N2	-	-

Subunits

EC Number	Subunits	Comment	Organism
1.1.1.42	dimer	and tetramer, crystallization data and analytical ultracentrifugation	Thermotoga maritima
1.1.1.42	tetramer	and dimer, crystallization data and analytical ultracentrifugation	Thermotoga maritima

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Release 2023.1 (January 2023)