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Literature summary extracted from

  • Fonseca, F.V.; Fonseca de Souza, A.L.; Mariano, A.C.; Entringer, P.F.; Gondim, K.C.; Meyer-Fernandes, J.R.
    Trypanosoma rangeli: characterization of a Mg-dependent ecto ATP-diphosphohydrolase activity (2006), Exp. Parasitol., 112, 76-84.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.1.5 lipophorin
-
 Trypanosoma rangeli
3.6.1.5 MgCl2 stimulation in intact parasite Trypanosoma rangeli
3.6.1.5 MnCl2 stimulation in intact parasite, may substitute for MgCl2 Trypanosoma rangeli
3.6.1.5 additional information not stimulatory: CaCl2, SrCl2, ZnCl2 Trypanosoma rangeli

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid
-
 Trypanosoma rangeli
3.6.1.5 additional information not inhibitory: oligomycin, sodium azide, bafilomycin A1, ouabain, furosemide, vanadate, molybdate, sodium fluoride, tartrate, levamizole Trypanosoma rangeli
3.6.1.5 suramin
-
 Trypanosoma rangeli

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Trypanosoma rangeli
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.5 additional information
-
 Mg2+-stimulated activity in intact parasite is 5.24 nmol Pi per h and 10000000 cells Trypanosoma rangeli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ADP + H2O 37.7% of the activity with ATP Trypanosoma rangeli AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O
-
 Trypanosoma rangeli AMP + 2 phosphate
-
 ?
3.6.1.5 CTP + H2O 17.4% of the activity with ATP Trypanosoma rangeli CDP + phosphate
-
 ?
3.6.1.5 GTP + 2 H2O 51.4% of the activity with ATP Trypanosoma rangeli GMP + 2 phosphate
-
 ?
3.6.1.5 ITP + 2 H2O 84.8% of the activity with ATP Trypanosoma rangeli IMP + 2 phosphate
-
 ?
3.6.1.5 UTP + 2 H2O 25.2% of the activity with ATP Trypanosoma rangeli UMP + 2 phosphate
-
 ?