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Literature summary extracted from
- Retinoid metabolism in the rat small intestine (2005), Br. J. Nutr., 93, 59-63.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.1.71 | cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.71 | retinaldehyde + NADH | Rattus norvegicus | the enzyme is involved in retinol and vitamin A metabolism, retinoic acid is important in intestinal epithelial cell proliferation and differentiation, the enzyme also plays a role in dietary conversion of beta-carotene to retinol via retinaldehyde | retinol + NAD+ | - |
r |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.71 | Rattus norvegicus | - |
adult female and male Wistar rats | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.71 | epithelial cell | small intestine | Rattus norvegicus | - |
| 1.1.1.71 | small intestine | - |
Rattus norvegicus | - |
| 1.1.1.71 | villus | small intestine | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.71 | retinaldehyde + NADH | - |
Rattus norvegicus | retinol + NAD+ | - |
r | |
| 1.1.1.71 | retinaldehyde + NADH | the enzyme is involved in retinol and vitamin A metabolism, retinoic acid is important in intestinal epithelial cell proliferation and differentiation, the enzyme also plays a role in dietary conversion of beta-carotene to retinol via retinaldehyde | Rattus norvegicus | retinol + NAD+ | - |
r | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.1.71 | retinaldehyde reductase | - |
Rattus norvegicus |
| 1.1.1.71 | Retinol dehydrogenase | - |
Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.71 | 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.71 | 7.4 | - |
assay at | Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.71 | NAD+ | - |
Rattus norvegicus | |
| 1.1.1.71 | NADH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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