Literature summary extracted from

Thimon, V.; Metayer, S.; Belghazi, M.; Dacheux, F.; Dacheux, J.L.; Gatti, J.L.
Shedding of the germinal angiotensin I-converting enzyme (gACE) involves a serine protease and is activated by epididymal fluid (2005), Biol. Reprod., 73, 881-890.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.4.15.1	soluble	-	Ovis aries	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.15.1	Ovis aries	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
3.4.15.1	proteolytic modification	the soluble germinal angiotensin I-convering enzyme results from an active proteolytic process that releases the enzyme's extracellular domain from sperm in a precise spatiotemporal location during epididymal transit. This process involves serine protease activity. The cleavage site is Arg622-Leu623 of the mature sheep germinal angiotensin I-converting enzyme. Thereafter, the C-terminal Arg is removed, leaving Ala621 as a C-terminal	Ovis aries

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.15.1	-	Ovis aries

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.15.1	epididymal fluid	-	Ovis aries	-

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Release 2023.1 (January 2023)