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Literature summary extracted from
- cDNA cloning and expression of biologically active platelet activating factor-acetylhydrolase (PAF-AH) from bovine mammary gland (2005), Biol. Pharm. Bull., 28, 580-583.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.1.47 | active enzyme expressed in HEK 293 cells | Bos taurus |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.47 | 43000 | - |
1 * 43000, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.47 | 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | Bos taurus | regulation of platelet-activating factor, protection against toxic effects of platelet-activating factor | 1-O-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? |  |
| 3.1.1.47 | oxidized phospholipids + H2O | Bos taurus | protection against toxic effects of oxidized phospholipids | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.47 | Bos taurus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.47 | mammary gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.47 | 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | regulation of platelet-activating factor, protection against toxic effects of platelet-activating factor | Bos taurus | 1-O-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? | |
| 3.1.1.47 | oxidized phospholipids + H2O | protection against toxic effects of oxidized phospholipids | Bos taurus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.1.47 | monomer | 1 * 43000, SDS-PAGE | Bos taurus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.47 | PAF-acetylhydrolase | - |
Bos taurus |
| 3.1.1.47 | PAF-AH | - |
Bos taurus |
| 3.1.1.47 | platelet activating factor-acetylhydrolase | - |
Bos taurus |
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Release 2023.1 (January 2023)
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