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Literature summary extracted from

  • Nomura, S.; Ito, T.; Yamamoto, E.; Sumigama, S.; Iwase, A.; Okada, M.; Shibata, K.; Ando, H.; Ino, K.; Kikkawa, F.; Mizutani, S.
    Gene regulation and physiological function of placental leucine aminopeptidase/oxytocinase during pregnancy (2005), Biochim. Biophys. Acta, 1751, 19-25.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.11.3
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.3 membrane type III integral membrane protein, converted to a soluble form existing in maternal serum by metalloproteases Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.3 angiotensin III + H2O Homo sapiens P-LAP/OTase may be involved in maintaining pregnancy homeostasis via metabolizing peptides such as oxytocin and vasopressin ?
-
 ?
3.4.11.3 Vasopressin + H2O Homo sapiens P-LAP/OTase may be involved in maintaining pregnancy homeostasis via metabolizing peptides such as oxytocin and vasopressin ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 blood serum type III integral membrane protein, converted to a soluble form existing in maternal serum by metalloproteases Homo sapiens
-
3.4.11.3 placenta predominantly expressed in differentiated trophoblasts, syncytiotrophoblasts Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.3 angiotensin III + H2O
-
 Homo sapiens ?
-
 ?
3.4.11.3 angiotensin III + H2O P-LAP/OTase may be involved in maintaining pregnancy homeostasis via metabolizing peptides such as oxytocin and vasopressin Homo sapiens ?
-
 ?
3.4.11.3 Vasopressin + H2O
-
 Homo sapiens ?
-
 ?
3.4.11.3 Vasopressin + H2O P-LAP/OTase may be involved in maintaining pregnancy homeostasis via metabolizing peptides such as oxytocin and vasopressin Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.3 P-LAP/OTase
-
 Homo sapiens
3.4.11.3 placental leucine aminopeptidase/oxytocinase
-
 Homo sapiens