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Literature summary extracted from

  • Guerra de Gonzalez, L.; Gonzalez de Alfonzo, R.; Lippo de Becemberg, I.; Alfonzo, M.J.
    Cyclic nucleotide-dependent phosphodiesterases (PDEI) inhibition by muscarinic antagonists in bovine tracheal smooth muscle (2004), Biochem. Pharmacol., 68, 651-658.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.17 additional information Bos taurus muscarinic antagonists acting possibly as inverse agonists on M2/M3 muscarinic acetylcholine receptors anchored to sarcolemma membranes can initiate a new signal transducing cascade leading to inhibition of PDEI, which produces a simultaneous rise in both cAMP and cGMP intracellular levels in tracheal smooth muscle ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Bos taurus
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.17 tracheal smooth muscle
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 Bos taurus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 additional information muscarinic antagonists acting possibly as inverse agonists on M2/M3 muscarinic acetylcholine receptors anchored to sarcolemma membranes can initiate a new signal transducing cascade leading to inhibition of PDEI, which produces a simultaneous rise in both cAMP and cGMP intracellular levels in tracheal smooth muscle Bos taurus ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.17 PDEI
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 Bos taurus