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Literature summary extracted from

  • Hu, J.; Van den Steen, P.E.; Houde, M.; Ilenchuk, T.T.; Opdenakker, G.
    Inhibitors of gelatinase B/matrix metalloproteinase-9 activity. Comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody (2004), Biochem. Pharmacol., 67, 1001-1009.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.35 1,10-phenanthroline 10 mM, 100% inhibition Homo sapiens
3.4.24.35 D-penicillamine 10 mg/l, 43% inhibition Homo sapiens
3.4.24.35 EDTA 10 mM, 74% inhibition Homo sapiens
3.4.24.35 polyhistidine 0.001 mM, 68% inhibition Homo sapiens
3.4.24.35 REGA-3G12 scFv with (His6)2 monoclonal antibody REGA-3G12 single-chain variable fragment, 0.005 mM, 66% inhibition Homo sapiens
3.4.24.35 Tissue inhibitor of metalloproteinase-1 1 nM, 88% inhibition Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.35 Homo sapiens
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.35 Ac-L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-NH2 + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.35 L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-NH2 + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.35 additional information no substrate: L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala(CH3)-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-CONH2 Homo sapiens ?
-
 ?