EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.21 | additional information | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells, overview | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.21 | aldose + NADPH + H+ | Homo sapiens | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells can lead to cell damage and pulmonary disease, overview | alditol + NADP+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.21 | Homo sapiens | P15121 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.21 | A-549 cell | type II alveolar epithelial cell line, AR expression analysis | Homo sapiens | - |
1.1.1.21 | lung | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.21 | aldose + NADPH + H+ | - |
Homo sapiens | alditol + NADP+ | - |
? | |
1.1.1.21 | aldose + NADPH + H+ | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells can lead to cell damage and pulmonary disease, overview | Homo sapiens | alditol + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.21 | AKR1B1 | - |
Homo sapiens |
1.1.1.21 | aldose reductase | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.21 | NADPH | - |
Homo sapiens |