Literature summary extracted from

Yao, H.; Hersh, L.B.
Characterization of the binding of the fluorescent ATP analog TNP-ATP to insulysin (2006), Arch. Biochem. Biophys., 451, 175-181.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.4.24.56	2',3'-O-(2,4,6-trinitrophenyl)adenosine triphosphate	about 15fold activation, 50% activation at o.0016 mM, activation is inhibited by Mg2+	Rattus norvegicus
3.4.24.56	ADP	inhibition of binding of 2,3-O-(2,4,6-trinitrophenyl)adenosine triphosphate with Ki-value 2.2 mM	Rattus norvegicus
3.4.24.56	ATP	50% activation at 1.4 mM, activation is inhibited by Mg2+. Inhibition of binding of 2,3-O-(2,4,6-trinitrophenyl)adenosine triphosphate with Ki-value 1.3 mM	Rattus norvegicus
3.4.24.56	Triphosphate	inhibition of binding of 2,3-O-(2,4,6-trinitrophenyl)adenosine triphosphate with Ki-value 0.9 mM	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.56	Rattus norvegicus	-	recombinant enzyme	-

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Release 2023.1 (January 2023)