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Literature summary extracted from

  • Nishimasu, H.; Fushinobu, S.; Shoun, H.; Wakagi, T.
    The first crystal structure of the novel class of fructose-1,6-bisphosphatase present in thermophilic archaea (2004), Structure, 12, 949-959.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.1.3.11 structure contains an unhydrolized substrate molecule in open-keto form, and four hexacoordinated magnesium ions Sulfurisphaera tokodaii

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.11 Mn2+ inhibitory above 3 mM Sulfurisphaera tokodaii
3.1.3.11 Zn2+ inhibitory above 3 mM Sulfurisphaera tokodaii

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.11 Mg2+ absolute requirement for divalent cation, fulfilled by Mg2+, Zn2+, Mn2+, maximum activity at 5 mM. Four molecules per homooctamer, crystallization data Sulfurisphaera tokodaii
3.1.3.11 Mn2+ absolute requirement for divalent cation, fulfilled by Mg2+, Zn2+, Mn2+, both Zn2+ and Mn2+ are inhibitory above 3 mM Sulfurisphaera tokodaii
3.1.3.11 Zn2+ absolute requirement for divalent cation, fulfilled by Mg2+, Zn2+, Mn2+, both Zn2+ and Mn2+ are inhibitory above 3 mM Sulfurisphaera tokodaii

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.11 Sulfurisphaera tokodaii
-
-
-
3.1.3.11 Sulfurisphaera tokodaii 7
-
-
-

Subunits

EC Number Subunits Comment Organism
3.1.3.11 octamer crystallization data Sulfurisphaera tokodaii

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.3.11 100
-
 and above, highly thermophilic enzyme Sulfurisphaera tokodaii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.11 8
-
-
 Sulfurisphaera tokodaii