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Literature summary extracted from

  • Basset, G.J.; Ravanel, S.; Quinlivan, E.P.; White, R.; Giovannoni, J.J.; Rebeille, F.; Nichols, B.P.; Shinozaki, K.; Seki, M.; Gregory, J.F., 3rd; Hanson, A.D.
    Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase (2004), Plant J., 40, 453-461.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.3.38 cDNAs are shown to encode functional enzymes by complementation of an Escherichia coli pabC mutant, and by demonstrating that the partially purified recombinant proteins convert 4-amino-4-deoxychorismate to 4-aminobenzoate Solanum lycopersicum
4.1.3.38 cDNAs are shown to encode functional enzymes by complementation of an Escherichia coli pabC mutant, and by demonstrating that the partially purified recombinant proteins convert 4-amino-4-deoxychorismate to 4-aminobenzoate. The full-length Arabidopsis ADC lyase polypeptide is translocated into isolated pea chloroplasts and, when fused to green fluorescent protein, directed the passenger protein to Arabidopsis chloroplasts in transient expression experiments Arabidopsis thaliana

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.3.38 additional information no feedback inhibition by physiological concentrations of 4-aminobenzoate, its glucose ester, or folates Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.3.38 plastid
-
 Arabidopsis thaliana 9536
-
4.1.3.38 plastid
-
 Solanum lycopersicum 9536
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.3.38 4-amino-4-deoxychorismate Arabidopsis thaliana last step of the 4-aminobenzoate branch 4-aminobenzoate + pyruvate
-
 ?
4.1.3.38 4-amino-4-deoxychorismate Solanum lycopersicum last step of the 4-aminobenzoate branch 4-aminobenzoate + pyruvate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.3.38 Arabidopsis thaliana
-
-
-
4.1.3.38 Solanum lycopersicum
-
 Mill. cv. Micro-Tom
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.3.38 4-amino-4-deoxychorismate last step of the 4-aminobenzoate branch Arabidopsis thaliana 4-aminobenzoate + pyruvate
-
 ?
4.1.3.38 4-amino-4-deoxychorismate last step of the 4-aminobenzoate branch Solanum lycopersicum 4-aminobenzoate + pyruvate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.3.38 ADC lyase
-
 Arabidopsis thaliana
4.1.3.38 ADC lyase
-
 Solanum lycopersicum