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Literature summary extracted from

  • Hitchcock, T.M.; Gao, H.; Cao, W.
    Cleavage of deoxyoxanosine-containing oligodeoxyribonucleotides by bacterial endonuclease V (2004), Nucleic Acids Res., 32, 4071-4080.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.21.7 Co2+ supports oxanosine-containing DNA cleavage to a small extent Salmonella sp.
3.1.21.7 Mg2+ supports oxanosine-containing DNA cleavage Salmonella sp.
3.1.21.7 Mn2+ supports oxanosine-containing DNA cleavage Salmonella sp.
3.1.21.7 Ni2+ supports oxanosine-containing DNA cleavage to a small extent Salmonella sp.

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.7 Salmonella sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.7 DNA + H2O the enzyme can cleave oxanosine-containing DNA at the second phosphodiester bond 3' to the lesion. All four oxanosine-containing base pairs (A/O), T/O, C/O and G/O are cleaved with similar efficiency. The cleavage of double-stranded oxanosine-containing DNA is about 6fold less efficient than that of double-stranded inosine-containing DNA. Single-stranded oxanosine-containing DNA is cleaved with a lower efficiency as compared with double-stranded oxanosine-containing DNA Salmonella sp. ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.21.7 endonuclease V
-
 Salmonella sp.