Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mishra, O.P.; Delivoria-Papadopoulos, M.
    ATP and cytochrome c-dependent inhibition of caspase-9 activity in the cerebral cortex of newborn piglets (2004), Neurosci. Lett., 364, 119-123.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.62 ATP enzyme activity is inhibited in both normoxic and hypoxic groups. The IC50 increases 5fold following hypoxia, suggesting a hypoxia-induced modification of the ATP binding site. 70% inhibition by 1 mM Sus scrofa
3.4.22.62 cytochrome c enzyme activity is inhibited in both normoxic and hypoxic groups. The IC50 increases 1.5fold following hypoxia, suggesting a hypoxia-induced modification of the cytochrome binding site. 70% inhibition by 0.003 mM Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.62 Sus scrofa
-
newborn piglet
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.62 cerebral cortex of newborn piglets Sus scrofa
-