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Literature summary extracted from
- Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence (2005), Nat. Med., 11, 638-644.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | medicine | isocitrate lyase inhibitors as possible antituberculosis drugs | Mycobacterium tuberculosis |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | 3-nitropropionate | no growth of Mycobacterium tuberculosis on fatty acids after addition of 3-nitropropionate | Mycobacterium tuberculosis |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.1 | Mycobacterium tuberculosis | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | ICL | - |
Mycobacterium tuberculosis |
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Release 2023.1 (January 2023)
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