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Literature summary extracted from

  • Pendergraft, W.F.3rd.; Rudolph, E.H.; Falk, R.J.; Jahn, J.E.; Grimmler, M.; Hengst, L.; Jennette, J.C.; Preston, G.A.
    Proteinase 3 sidesteps caspases and cleaves p21 Waf1/Cip1/Sdi1 to induce endothelial cell apoptosis (2004), Kidney Int., 65, 75-84.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.76 diisopropylfluorophosphate irreversible inhibition Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.76 Homo sapiens P24158
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.76
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.76 HUVEC cell
-
 Homo sapiens
-
3.4.21.76 neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.76 BID + H2O 37°C, Bid = BH3 interacting domain death agonist Homo sapiens ?
-
 ?
3.4.21.76 nuclear factor-kappaB + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.76 p21 + H2O 37°C, cleavage occurs between Thr80 and Gly81 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.76 PR3
-
 Homo sapiens
3.4.21.76 proteinase 3
-
 Homo sapiens