Literature summary extracted from

Safarian, S.; Moosavi-Movahedi, A.A.; Hosseinkhani, S.; Xia, Z.; Habibi-Rezaei, M.; Hosseini, G.; Sorenson, C.; Sheibani, N.
The structural and functional studies of His119 and His12 in RNase A via chemical modification (2003), J. Protein Chem., 22, 643-654.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.6.1.18	diethylpyrocarbonate	among the His residues of RNase A, His48 is not accessible to react with diethylpyrocarbonate	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.6.1.18	Bos taurus	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
4.6.1.18	an [RNA] containing cytidine + H2O = an [RNA]-3'-cytidine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA]	His119 and His12 play an important structural role in active site of RNase A	Bos taurus	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)