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Literature summary extracted from
- Cloning of human liver cytosolic sialidase from genomic DNA using splicing by overlap extension and its characterization (2005), J. Microbiol. Biotechnol., 15, 722-727.
No PubMed abstract available
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.2.1.18 | - |
Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.18 | Cd2+ | - |
Homo sapiens |  |
| 3.2.1.18 | Cu2+ | - |
Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.2.1.18 | cytosol | - |
Homo sapiens | 5829 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 42000 | - |
- |
Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.18 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.18 | recombinant His-tagged protein | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.18 | liver | - |
Homo sapiens | - |
| 3.2.1.18 | skeletal muscle | poor expression | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.18 | 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
Homo sapiens | 4-methylumbelliferone + alpha-D-N-acetylneuraminic acid | - |
? | |
| 3.2.1.18 | alpha2,3-sialyllactose + H2O | - |
Homo sapiens | sialic acid + lactose | - |
? | |
| 3.2.1.18 | fetuin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | ganglioside GD1a + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | ganglioside GD1b + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | ganglioside GD3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | ganglioside GM3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | additional information | hardly any activities on alpha(2-6)-sialyllactose and ganglioside GM1 and GM2 | Homo sapiens | ? | - |
? | |
| 3.2.1.18 | orosomucoid + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | transferrin + H2O | - |
Homo sapiens | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 37.5 | - |
- |
Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 6 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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