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Literature summary extracted from

  • Abe, M.; Shibata, K.; Urata, H.; Sakata, N.; Katsuragi, T.
    Induction of leukotriene C4 synthase after the differentiation of rat basophilic leukemia cells with retinoic acid and a low dose of actinomycin D and its suppression with methylprednisolone (2003), J. Cell. Physiol., 196, 154-164.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.4.1.20 actinomycin D in addition to retinoic acid Rattus norvegicus
4.4.1.20 daunorubicin
-
 Rattus norvegicus
4.4.1.20 mitomycin C
-
 Rattus norvegicus
4.4.1.20 retinoic acid
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.20 18000
-
 x * 18000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.20 leukotriene C4 Rattus norvegicus
-
 leukotriene A4 + glutathione
-
 r

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.20 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.20 RBL-1 cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.20 leukotriene A4 free acid + glutathione pH 7.4, 37°C Rattus norvegicus leukotriene C4
-
 r
4.4.1.20 leukotriene A4 methylester + glutathione pH 7.4, 37°C Rattus norvegicus leukotriene C4 methylester
-
 r
4.4.1.20 leukotriene C4
-
 Rattus norvegicus leukotriene A4 + glutathione
-
 r

Subunits

EC Number Subunits Comment Organism
4.4.1.20 ? x * 18000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
4.4.1.20 leukotriene C4 synthase
-
 Rattus norvegicus
4.4.1.20 LTC4S
-
 Rattus norvegicus