EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.22.70 | D170A | turnover-number for o-aminobenzoyl-LPETG-2,4-dinitrophenyl is nearly identical to wild-type value | Staphylococcus aureus |
3.4.22.70 | E108A | turnover-number for o-aminobenzoyl-LPETG-2,4-dinitrophenyl is 43.8fold lower than wild-type value | Staphylococcus aureus |
3.4.22.70 | E171A | turnover-number for o-aminobenzoyl-LPETG-2,4-dinitrophenyl is 4.7fold lower than wild-type value | Staphylococcus aureus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.22.70 | 0.00013 | - |
o-aminobenzoyl-LPETG-2,4-dinitrophenyl ester | mutant enzyme E108A | Staphylococcus aureus | |
3.4.22.70 | 0.0018 | - |
o-aminobenzoyl-LPETG-2,4-dinitrophenyl ester | mutant enzyme E171A | Staphylococcus aureus | |
3.4.22.70 | 0.0085 | - |
o-aminobenzoyl-LPETG-2,4-dinitrophenyl ester | wild-type enzyme | Staphylococcus aureus | |
3.4.22.70 | 0.0087 | - |
o-aminobenzoyl-LPETG-2,4-dinitrophenyl ester | mutant enzyme D170A | Staphylococcus aureus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.70 | Ca2+ | a single Ca2+ bound to an ordered pocket on SrtA allosterically activates catalysis by modulating both the structure and dynamics of a large active site loop | Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.70 | Staphylococcus aureus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.22.70 | - |
Staphylococcus aureus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.70 | o-aminobenzoyl-LPETG-2,4-dinitrophenyl ester + H2O | - |
Staphylococcus aureus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.70 | sortase A transpeptidase | - |
Staphylococcus aureus |