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Literature summary extracted from
- The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes (2005), J. Biol. Chem., 280, 38125-38132.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.2.3 | 13.3 | - |
succinyl-CoA | - |
Mus musculus |  |
| 3.1.2.3 | 37.1 | - |
glutaryl-CoA | - |
Mus musculus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.2.3 | peroxisome | - |
Mus musculus | 5777 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.3 | additional information | Mus musculus | enzyme is responsible for the termination of beta-oxidation of dicarboxylic acids of medium chain length | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.2.3 | Mus musculus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.1.2.3 | additional information | sequence contains a putative consensus type 1 peroxisome targeting signal | Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.2.3 | kidney | - |
Mus musculus | - |
| 3.1.2.3 | liver | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.3 | 1.14 | - |
substrate glutaryl-CoA | Mus musculus |
| 3.1.2.3 | 3.98 | - |
substrate succinyl-CoA | Mus musculus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.3 | glutaryl-CoA + H2O | - |
Mus musculus | CoA + glutarate | - |
? | |
| 3.1.2.3 | additional information | enzyme is responsible for the termination of beta-oxidation of dicarboxylic acids of medium chain length | Mus musculus | ? | - |
? | |
| 3.1.2.3 | succinyl CoA + H2O | - |
Mus musculus | CoA + succinate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.2.3 | acetyl-CoA thioesterase | - |
Mus musculus |
| 3.1.2.3 | ACOT4 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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