Literature summary extracted from

Marraffini, L.A.; Schneewind, O.
Anchor structure of staphylococcal surface proteins. V. Anchor structure of the sortase B substrate IsdC (2005), J. Biol. Chem., 280, 16263-16271.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.22.71	IsdC + H2O	Staphylococcus aureus	the enzyme anchors the IsdC precursor with a C-terminal NPQTN motif sorting sognal, to the cell wall envelope. The sorting signal of IsdC is cleaved between threonine and asparagine of the NPQTN motif, and the carboxyl group of the thrteonine is amide-linked to the amino group of pentaglycine cross-bridges	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.71	Staphylococcus aureus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.22.71	IsdC + H2O	the enzyme anchors the IsdC precursor with a C-terminal NPQTN motif sorting sognal, to the cell wall envelope. The sorting signal of IsdC is cleaved between threonine and asparagine of the NPQTN motif, and the carboxyl group of the thrteonine is amide-linked to the amino group of pentaglycine cross-bridges	Staphylococcus aureus	?	-	?

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Release 2023.1 (January 2023)