Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Revill, W.P.; Bibb, M.J.; Scheu, A.K.; Kieser, H.J.; Hopwood, D.A.
    beta-Ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2) (2001), J. Bacteriol., 183, 3526-3530.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.180 additional information the acpP gene product stimulates fatty acid biosynthesis in vitro Streptomyces coelicolor

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.180 gene fabH is transcribed in a gene cluster to produce a leaderless mRNA transcript, transcription analysis, genetic organization, overview Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein] Streptomyces coelicolor
-
 acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein] Streptomyces coelicolor A3(2)
-
 acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 additional information Streptomyces coelicolor the enzyme is responsible for the initiation of fatty acid biosynthesis and for viability ?
-
 ?
2.3.1.180 additional information Streptomyces coelicolor A3(2) the enzyme is responsible for the initiation of fatty acid biosynthesis and for viability ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.180 Streptomyces coelicolor P72392 gene fabH
-
2.3.1.180 Streptomyces coelicolor A3(2) P72392 gene fabH
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein]
-
 Streptomyces coelicolor acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein] the enzyme prefers long-chain fatty acids Streptomyces coelicolor acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein]
-
 Streptomyces coelicolor A3(2) acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acyl-CoA + malonyl-[acyl-carrier protein] the enzyme prefers long-chain fatty acids Streptomyces coelicolor A3(2) acetoacyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 additional information the enzyme is responsible for the initiation of fatty acid biosynthesis and for viability Streptomyces coelicolor ?
-
 ?
2.3.1.180 additional information the enzyme is responsible for the initiation of fatty acid biosynthesis and for viability Streptomyces coelicolor A3(2) ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.180 beta-ketoacyl acyl carrier protein synthase III
-
 Streptomyces coelicolor
2.3.1.180 FabH
-
 Streptomyces coelicolor