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Literature summary extracted from

  • Hale, L.P.
    Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice (2004), Int. Immunopharmacol., 4, 255-264.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.22.32 medicine oral bromelain may potentially modify inflammation within the gastrointestinal tract via local proteolytic activity within the colonic microenvironment Ananas comosus

General Stability

EC Number General Stability Organism
3.4.22.32 the low bromelain activity, particularly in the upper portion of the murine gastrointestinal tract, following oral administration, suggests that extensive gastric inactivation of bromelain may occur in vivo. When formulated in antacid, oral bromelain retains substantial proteolytic activity throughout the gastrointestinal tract (of mice) Ananas comosus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.32 Ananas comosus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.32 stem
-
Ananas comosus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.32 benzyloxycarbonyl-Arg-Arg-p-nitroanilide + H2O
-
Ananas comosus benzyloxycarbonyl-Arg-Arg + p-nitroaniline
-
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