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Literature summary extracted from

  • Hamilton, S.R.; Li, H.; Wischnewski, H.; Prasad, A.; Kerley-Hamilton, J.S.; Mitchell, T.; Walling, A.J.; Davidson, R.C.; Wildt, S.; Gerngross, T.U.
    Intact alpha-1,2-endomannosidase is a typical type II membrane protein (2005), Glycobiology, 15, 615-624.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.130 expression in Pichia pastoris Rattus norvegicus
3.2.1.130 expression in Pichia pastoris Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.130 Golgi membrane
-
 Rattus norvegicus 139
-
3.2.1.130 Golgi membrane
-
 Homo sapiens 139
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.130 55000
-
 x * 55000, SDS-PAGE Homo sapiens
3.2.1.130 59000
-
 x * 59000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.130 Homo sapiens Q5SRI9
-
-
3.2.1.130 Rattus norvegicus Q5GF25
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.130 brain
-
 Rattus norvegicus
-
3.2.1.130 brain
-
 Homo sapiens
-
3.2.1.130 heart
-
 Rattus norvegicus
-
3.2.1.130 heart
-
 Homo sapiens
-
3.2.1.130 kidney
-
 Rattus norvegicus
-
3.2.1.130 kidney
-
 Homo sapiens
-
3.2.1.130 liver most prominent Rattus norvegicus
-
3.2.1.130 liver most prominent Homo sapiens
-
3.2.1.130 lung
-
 Rattus norvegicus
-
3.2.1.130 lung
-
 Homo sapiens
-
3.2.1.130 muscle
-
 Rattus norvegicus
-
3.2.1.130 muscle
-
 Homo sapiens
-
3.2.1.130 pancreas
-
 Rattus norvegicus
-
3.2.1.130 pancreas
-
 Homo sapiens
-
3.2.1.130 placenta
-
 Rattus norvegicus
-
3.2.1.130 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.130 GlcMan5GlcNAc2 + H2O 37°C Rattus norvegicus alpha-D-glucosyl-1,3-D-mannopyranose + Man4GlcNAc2
-
 ?
3.2.1.130 GlcMan5GlcNAc2 + H2O 37°C Homo sapiens alpha-D-glucosyl-1,3-D-mannopyranose + Man4GlcNAc2
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.130 ? x * 55000, SDS-PAGE Homo sapiens
3.2.1.130 ? x * 59000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
3.2.1.130 alpha-1,2-endomannosidase
-
 Rattus norvegicus
3.2.1.130 alpha-1,2-endomannosidase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.130 37
-
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.130 6.2
-
-
 Homo sapiens