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Literature summary extracted from

  • Owaga, Y.; Mamura, Y.; Murayama, N.; Yanoshita, R.
    Characterization and cDNA cloning of dipeptidyl peptidase IV from the venom of Gloydius blomhoffi brevicaudatus (2006), Comp. Biochem. Physiol. B, 145, 35-42.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.14.5
-
Gloydius brevicaudus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.14.5 diisopropylfluorophosphate 1 mM, complete inhibition; 1 mM, complete inhibition Gloydius brevicaudus
3.4.14.5 additional information no inhibition by 5 mM EDTA or 0.005 mg/ml leupeptin; no inhibition by 5 mM EDTA or 0.005 mg/ml leupeptin Gloydius brevicaudus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.14.5 116000
-
x * 116000, SDS-PAGE Gloydius brevicaudus

Organism

EC Number Organism UniProt Comment Textmining
3.4.14.5 Gloydius brevicaudus Q75S82 dipeptidylpeptidase 4b
-
3.4.14.5 Gloydius brevicaudus Q75S83 dipeptidylpeptidase 4a
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.14.5 partial Gloydius brevicaudus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.14.5 venom
-
Gloydius brevicaudus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.14.5 0.0598
-
-
Gloydius brevicaudus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.14.5 Gly-Pro-4-methylcoumarin 7-amide + H2O
-
Gloydius brevicaudus Gly-Pro + 7-amino-4-methylcoumarin
-
?
3.4.14.5 Lys-Ala-4-methylcoumarin 7-amide + H2O 8.7% of the activity with Pro-4-methylcoumarin 7-amide Gloydius brevicaudus Lys-Ala + 7-amino-4-methylcoumarin
-
?
3.4.14.5 Phe-Pro-4-methylcoumarin 7-amide + H2O 108.6% of the activity with Pro-4-methylcoumarin 7-amide Gloydius brevicaudus Phe-Pro + 7-amino-4-methylcoumarin
-
?

Subunits

EC Number Subunits Comment Organism
3.4.14.5 ? x * 116000, SDS-PAGE Gloydius brevicaudus

Synonyms

EC Number Synonyms Comment Organism
3.4.14.5 dipeptidylpeptidase 4a
-
Gloydius brevicaudus
3.4.14.5 dipeptidylpeptidase 4b
-
Gloydius brevicaudus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.14.5 50
-
stable up to Gloydius brevicaudus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.14.5 8.5
-
-
Gloydius brevicaudus