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Literature summary extracted from

  • Itoh, R.; Kimura, K.
    IMP-GMP 5'-nucleotidase in reptiles: Occurrence and tissue distribution in a crocodile and three species of lizards (2005), Comp. Biochem. Physiol. B, 142B, 107-112.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.5 0.41
-
 5'-inosinic acid 37°C, pH 7.5 Salvator rufescens
3.1.3.5 0.58
-
 5'-inosinic acid 37°C, pH 7.5 Varanus gouldii
3.1.3.5 0.83
-
 5'-inosinic acid 37°C, pH 7.5 Crocodylus siamensis
3.1.3.5 7.1
-
 5'-AMP 37°C, pH 7.5 Salvator rufescens
3.1.3.5 7.3
-
 5'-AMP 37°C, pH 7.5 Varanus gouldii
3.1.3.5 13.6
-
 5'-AMP 37°C, pH 7.5 Crocodylus siamensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.5 additional information Varanus gouldii high enzyme activity in liver is a feature of constitutive uricotelism, enzyme may participate in the production of uric acid ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.5 Crocodylus siamensis
-
-
-
3.1.3.5 Salvator rufescens
-
-
-
3.1.3.5 Varanus gouldii
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.5 kidney
-
 Salvator rufescens
-
3.1.3.5 liver
-
 Crocodylus siamensis
-
3.1.3.5 liver
-
 Varanus gouldii
-
3.1.3.5 additional information high enzyme activity in decreasing order: kidney, liver, testis, spleen Salvator rufescens
-
3.1.3.5 additional information high enzyme activity in decreasing order: liver, kidney, spleen Crocodylus siamensis
-
3.1.3.5 additional information high enzyme activity in decreasing order: liver, kidney, spleen Varanus gouldii
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.5 1-glycerophosphate + H2O 1% of the activity with 5’-IMP Varanus gouldii glycerol + phosphate
-
 ?
3.1.3.5 5'-AMP + H2O 17% of the activity with 5’-IMP Crocodylus siamensis adenosine + phosphate
-
 ?
3.1.3.5 5'-AMP + H2O 30% of the activity with 5’-IMP Salvator rufescens adenosine + phosphate
-
 ?
3.1.3.5 5'-AMP + H2O 32% of the activity with 5’-IMP Varanus gouldii adenosine + phosphate
-
 ?
3.1.3.5 5'-CMP + H2O 11% of the activity with 5’-IMP Varanus gouldii cytidine + phosphate
-
 ?
3.1.3.5 5'-CMP + H2O 17% of the activity with 5’-IMP Salvator rufescens cytidine + phosphate
-
 ?
3.1.3.5 5'-CMP + H2O 21% of the activity with 5’-IMP Crocodylus siamensis cytidine + phosphate
-
 ?
3.1.3.5 5'-dIMP + H2O
-
 Crocodylus siamensis deoxyinosine + phosphate
-
 ?
3.1.3.5 5'-dIMP + H2O 102% of the activity with 5’-IMP Crocodylus siamensis deoxyinosine + phosphate
-
 ?
3.1.3.5 5'-dIMP + H2O 95% of the activity with 5’-IMP Salvator rufescens deoxyinosine + phosphate
-
 ?
3.1.3.5 5'-dIMP + H2O 99% of the activity with 5’-IMP Varanus gouldii deoxyinosine + phosphate
-
 ?
3.1.3.5 5'-dTMP + H2O 10% of the activity with 5’-IMP Varanus gouldii deoxythymidine + phosphate
-
 ?
3.1.3.5 5'-dTMP + H2O 17.5% of the activity with 5’-IMP Salvator rufescens deoxythymidine + phosphate
-
 ?
3.1.3.5 5'-dTMP + H2O 7.1% of the activity with 5’-IMP Crocodylus siamensis deoxythymidine + phosphate
-
 ?
3.1.3.5 5'-GMP + H2O 104% of the activity with 5’-IMP Varanus gouldii guanosine + phosphate
-
 ?
3.1.3.5 5'-GMP + H2O 89% of the activity with 5’-IMP Crocodylus siamensis guanosine + phosphate
-
 ?
3.1.3.5 5'-GMP + H2O 99% of the activity with 5’-IMP Salvator rufescens guanosine + phosphate
-
 ?
3.1.3.5 5'-IMP + H2O
-
 Varanus gouldii inosine + phosphate
-
 ?
3.1.3.5 5'-IMP + H2O
-
 Salvator rufescens inosine + phosphate
-
 ?
3.1.3.5 5'-IMP + H2O 8% of the activity with 5’-IMP Varanus gouldii inosine + phosphate
-
 ?
3.1.3.5 5'-inosinic acid + H2O
-
 Crocodylus siamensis ?
-
 ?
3.1.3.5 5'-UMP + H2O 33% of the activity with 5’-IMP Varanus gouldii uridine + phosphate
-
 ?
3.1.3.5 5'-UMP + H2O 41% of the activity with 5’-IMP Crocodylus siamensis uridine + phosphate
-
 ?
3.1.3.5 5'-UMP + H2O 56% of the activity with 5’-IMP Salvator rufescens uridine + phosphate
-
 ?
3.1.3.5 additional information high enzyme activity in liver is a feature of constitutive uricotelism, enzyme may participate in the production of uric acid Varanus gouldii ?
-
 ?
3.1.3.5 additional information no substrate: 3'-IMP, 1-glycerophosphate Crocodylus siamensis ?
-
 ?
3.1.3.5 additional information no substrate: 3'-IMP, 1-glycerophosphate Salvator rufescens ?
-
 ?