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Literature summary extracted from

  • Lin, R.; Liu, H.; Hao, J.; Cheng, K.; Liu, D.
    Enhancement of 1,3-propanediol production by Klebsiella pneumoniae with fumarate addition (2005), Biotechnol. Lett., 27, 1755-1759.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.202 fumarate 25% activation of the enzyme, enhances the production of 1,3-propanediol from glycerol and the glycerol consumption in vivo Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.202 3-hydroxypropionaldehyde + NADH Klebsiella pneumoniae
-
propane-1,3-diol + NAD+
-
?
1.1.1.202 3-hydroxypropionaldehyde + NADH Klebsiella pneumoniae M5a1
-
propane-1,3-diol + NAD+
-
?
4.2.1.30 additional information Klebsiella pneumoniae activity of glycerol dehydratase is increased by 160%, 210% and 115% when, respectively, 5, 15 and 25 mM fumarate are provided ?
-
?
4.2.1.30 additional information Klebsiella pneumoniae M5a1 activity of glycerol dehydratase is increased by 160%, 210% and 115% when, respectively, 5, 15 and 25 mM fumarate are provided ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.202 Klebsiella pneumoniae
-
-
-
1.1.1.202 Klebsiella pneumoniae M5a1
-
-
-
4.2.1.30 Klebsiella pneumoniae
-
M5a1
-
4.2.1.30 Klebsiella pneumoniae M5a1
-
M5a1
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.202 3-hydroxypropionaldehyde + NADH
-
Klebsiella pneumoniae propane-1,3-diol + NAD+
-
?
1.1.1.202 3-hydroxypropionaldehyde + NADH
-
Klebsiella pneumoniae M5a1 propane-1,3-diol + NAD+
-
?
4.2.1.30 additional information activity of glycerol dehydratase is increased by 160%, 210% and 115% when, respectively, 5, 15 and 25 mM fumarate are provided Klebsiella pneumoniae ?
-
?
4.2.1.30 additional information activity of glycerol dehydratase is increased by 160%, 210% and 115% when, respectively, 5, 15 and 25 mM fumarate are provided Klebsiella pneumoniae M5a1 ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.202 1,3-propanediol oxidoreductase
-
Klebsiella pneumoniae
1.1.1.202 PDOR
-
Klebsiella pneumoniae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.202 9.7
-
assay at Klebsiella pneumoniae

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.202 NADH
-
Klebsiella pneumoniae