EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.22.70 | SrtADELTA24 is expressed in Escherichia coli | Staphylococcus aureus |
3.4.22.71 | SrtADELTA24 is expressed in Escherichia coli | Staphylococcus aureus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.70 | beta-sitosterol-3-O-glucopyranoside | - |
Staphylococcus aureus | |
3.4.22.70 | galangin | IC50 for recombinant SrtA(DELTA24): 0.123 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | galangin-3-methyl ether | IC50 for recombinant SrtA(DELTA24): 0.1179 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | isorhamnetin | IC50 for recombinant SrtA(DELTA24): 0.05886 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | kaempferol | IC50 for recombinant SrtA(DELTA24): 0.07794 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | morin | IC50 for recombinant SrtA(DELTA24): 0.03739 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | myricetin | IC50 for recombinant SrtA(DELTA24): 0.04403 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | quercetin | IC50 for recombinant SrtA(DELTA24): 0.0527 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.70 | quercetin-3,3'-dimethyl ether | IC50 for recombinant SrtA(DELTA24): 0.05361 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | galangin | IC50 for recombinant SrtB(DELTA30): 0.03837 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | galangin-3-methyl ether | IC50 for recombinant SrtB(DELTA30): 0.1136 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | isorhamnetin | IC50 for recombinant SrtB(DELTA30): 0.04335 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | kaempferol | IC50 for recombinant SrtB(DELTA30): 0.02455 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | morin | IC50 for recombinant SrtB(DELTA30): 0.00854 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | myricetin | IC50 for recombinant SrtB(DELTA30): 0.03689 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | quercetin | IC50 for recombinant SrtB(DELTA30): 0.03328 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
3.4.22.71 | quercetin-3,3'-dimethyl ether | IC50 for recombinant SrtB(DELTA30): 0.0603 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.70 | Staphylococcus aureus | - |
- |
- |
3.4.22.71 | Staphylococcus aureus | - |
- |
- |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.4.22.70 | 0.03739 | - |
IC50 for recombinant SrtA(DELTA24): 0.03739 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | morin | |
3.4.22.70 | 0.04403 | - |
IC50 for recombinant SrtA(DELTA24): 0.04403 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | myricetin | |
3.4.22.70 | 0.0527 | - |
IC50 for recombinant SrtA(DELTA24): 0.0527 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin | |
3.4.22.70 | 0.05361 | - |
IC50 for recombinant SrtA(DELTA24): 0.05361 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin-3,3'-dimethyl ether | |
3.4.22.70 | 0.05886 | - |
IC50 for recombinant SrtA(DELTA24): 0.05886 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | isorhamnetin | |
3.4.22.70 | 0.07794 | - |
IC50 for recombinant SrtA(DELTA24): 0.07794 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | kaempferol | |
3.4.22.70 | 0.1179 | - |
IC50 for recombinant SrtA(DELTA24): 0.1179 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin-3-methyl ether | |
3.4.22.70 | 0.123 | - |
IC50 for recombinant SrtA(DELTA24): 0.123 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin | |
3.4.22.71 | 0.00854 | - |
IC50 for recombinant SrtB(DELTA30): 0.00854 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | morin | |
3.4.22.71 | 0.02455 | - |
IC50 for recombinant SrtB(DELTA30): 0.02455 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | kaempferol | |
3.4.22.71 | 0.03328 | - |
IC50 for recombinant SrtB(DELTA30): 0.03328 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin | |
3.4.22.71 | 0.03689 | - |
IC50 for recombinant SrtB(DELTA30): 0.03689 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | myricetin | |
3.4.22.71 | 0.03837 | - |
IC50 for recombinant SrtB(DELTA30): 0.03837 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin | |
3.4.22.71 | 0.04335 | - |
IC50 for recombinant SrtB(DELTA30): 0.04335 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | isorhamnetin | |
3.4.22.71 | 0.0603 | - |
IC50 for recombinant SrtB(DELTA30): 0.0603 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin-3,3'-dimethyl ether | |
3.4.22.71 | 0.1136 | - |
IC50 for recombinant SrtB(DELTA30): 0.1136 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin-3-methyl ether |