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Literature summary extracted from

  • Dobson, R.C.; Griffin, M.D.; Roberts, S.J.; Gerrard, J.A.
    Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate (2004), Biochimie, 86, 311-315.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.3.3.7
-
 Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.3.7 (S)-lysine partial mixed inhibition with respect to its first substrate, pyruvate Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.3.7 0.11
-
 (S)-aspartate 4-semialdehyde 30°C Escherichia coli
4.3.3.7 0.26
-
 pyruvate 30°C Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
4.3.3.7 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.3.7
-
 Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.3.3.7 additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.3.7 (S)-aspartate 4-semialdehyde + pyruvate
-
 Escherichia coli dihydrodipicolinate + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.3.3.7 DHDPS
-
 Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.3.3.7 124
-
 pyruvate 30°C Escherichia coli
4.3.3.7 124
-
 (S)-aspartate 4-semialdehyde 30°C Escherichia coli

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.3.3.7 0.32
-
 (S)-lysine versus (S)-aspartate 4-semialdehyde Escherichia coli
4.3.3.7 3.9
-
 (S)-lysine versus pyruvate Escherichia coli