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Literature summary extracted from

  • Haiker, H.; Lengsfeld, H.; Hadvary, P.; Carriere, F.
    Rapid exchange of pancreatic lipase between triacylglycerol droplets (2004), Biochim. Biophys. Acta, 1682, 72-79.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.3 S152G inactive mutant, the inactive enzyme mutant S152G binds to tricaprylin in a water emulsion interface competiting with the active enzyme hydrolyzing the substrate, overview Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.3 orlistat
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.3 Homo sapiens
-
-
-
3.1.1.3 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.3 pancreas
-
 Homo sapiens
-
3.1.1.3 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.3 additional information the inactive enzyme mutant S152G binds to tricaprylin in a water emulsion interface competiting with the active enzyme hydrolyzing the substrate, overview Homo sapiens ?
-
 ?
3.1.1.3 tricaprylin + H2O
-
 Homo sapiens dicaprylin + caprylate
-
 ?
3.1.1.3 tricaprylin + H2O
-
 Sus scrofa dicaprylin + caprylate
-
 ?
3.1.1.3 triolein + H2O substrate is an olive oil/gum arabic emulsion containing radiolabeled triolein in presence of bile acids and lecithin at rate-limiting concentrations, rapid exchange of the enzyme between two different triacylglycerol droplets measured by a non-exchanging enzyme inhibitor in one of the droplets Sus scrofa diolein + oleate
-
 ?
3.1.1.3 triolein + H2O substrate is an olive oil/gum arabic emulsion containing radiolabeled triolein in presence of bile acids and lecithin at rate-limiting concentrations, rapid exchange of the enzyme between two different triacylglycerol droplets measured by a non-exchanging enzyme inhibitor orlistat in one of the droplets Homo sapiens diolein + oleate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.3 Pancreatic lipase
-
 Homo sapiens
3.1.1.3 Pancreatic lipase
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.3 37
-
 assay at Homo sapiens
3.1.1.3 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.3 7.5
-
 assay at Homo sapiens
3.1.1.3 7.5
-
 assay at Sus scrofa