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Literature summary extracted from

  • Florova, G.; Kazanina, G.; Reynolds, K.A.
    Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity (2002), Biochemistry, 41, 10462-10471.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.180 acetyl-CoA + malonyl-[acyl-carrier protein] Streptomyces glaucescens FabH initiates the elongation of straight-chain fatty acids by the fatty acid synthase II complex, fatty acid synthesis pathway overview acetoacetyl-[acyl-carrier protein] + CoA + CO2
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 ?
2.3.1.180 additional information Streptomyces glaucescens the enzyme is not directly involved in tetracenomycin C biosynthesis ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.180 Streptomyces glaucescens
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.180 acetyl-CoA + malonyl-[acyl-carrier protein] FabH initiates the elongation of straight-chain fatty acids by the fatty acid synthase II complex, fatty acid synthesis pathway overview Streptomyces glaucescens acetoacetyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acetyl-CoA + malonyl-[acyl-carrier protein] substrate malonyl-ACP is produced by FabC or Escherichia coli AcpP, but not by TcmM Streptomyces glaucescens acetoacetyl-[acyl-carrier protein] + CoA + CO2
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 ?
2.3.1.180 additional information the enzyme is not directly involved in tetracenomycin C biosynthesis Streptomyces glaucescens ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.180 FabH
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 Streptomyces glaucescens