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Literature summary extracted from

  • Gamberucci, A.; Konta, L.; Colucci, A.; Giunti, R.; Magyar, J.E.; Mandl, J.; Banhegyi, G.; Benedetti, A.; Csala, M.
    Green tea flavonols inhibit glucosidase II (2006), Biochem. Pharmacol., 72, 640-646.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.207 epicatechin gallate
-
 Rattus norvegicus
3.2.1.207 epigallocatechin
-
 Rattus norvegicus
3.2.1.207 epigallocatechin gallate
-
 Rattus norvegicus
3.2.1.207 gallocatechin
-
 Rattus norvegicus
3.2.1.207 gallocatechin gallate
-
 Rattus norvegicus
3.2.1.207 N-butyldeoxynojirimycin
-
 Rattus norvegicus
3.2.1.207 propyl gallate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.207 0.0552
-
 4-methylumbelliferyl-alpha-D-glucoside 37°C Rattus norvegicus
3.2.1.207 2.2
-
 4-nitrophenyl alpha-D-glucopyranoside 37°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.207 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.207 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.207 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.207 4-methylumbelliferyl-alpha-D-glucoside + H2O
-
 Rattus norvegicus 4-methylumbelliferone + alpha-D-glucose
-
 ?
3.2.1.207 4-nitrophenyl alpha-D-glucopyranoside + H2O
-
 Rattus norvegicus 4-nitrophenol + alpha-D-glucopyranose
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.2.1.207 0.002027
-
 gallocatechin gallate 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.002247
-
 N-butyldeoxynojirimycin 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.002545
-
 gallocatechin gallate 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.00519
-
 N-butyldeoxynojirimycin 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.008763
-
 epicatechin gallate 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.0131
-
 epicatechin gallate 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.02948
-
 epigallocatechin gallate 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.03281
-
 epigallocatechin gallate 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.03628
-
 propyl gallate 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.04312
-
 propyl gallate 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.06815
-
 epigallocatechin 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus
3.2.1.207 0.07062
-
 gallocatechin 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.07599
-
 epigallocatechin 37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside Rattus norvegicus
3.2.1.207 0.07893
-
 gallocatechin 37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside Rattus norvegicus