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Literature summary extracted from

  • Fillebeen, C.; Caltagirone, A.; Martelli, A.; Moulis, J.M.; Pantopoulos, K.
    IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities (2005), Biochem. J., 388, 143-150.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
4.2.1.3 S711E 45% of the capacity to catalyze conversion of cis-aconitase into isocitrate, completely fails to bind RNA and to generate isocitrate from citrate Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.3 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
4.2.1.3 phosphoprotein S711 is a phosphorylation site Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.3 recombinant IRP1 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.3 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.3 cis-aconitate + H2O
-
 Homo sapiens citrate
-
 ?
4.2.1.3 citrate
-
 Homo sapiens isocitrate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.3 iron regulatory protein 1
-
 Homo sapiens
4.2.1.3 IRP1
-
 Homo sapiens