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Literature summary extracted from

  • Cabezas, A.; Costas, M.J.; Pinto, R.M.; Couto, A.; Cameselle, J.C.
    Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases (2005), Biochem. Biophys. Res. Commun., 338, 1682-1689.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.29 expression in BL21 cells Homo sapiens
4.6.1.15 expression in BL21 cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.29 FAD inhibits the dihydroxyacetone kinase activity Homo sapiens
2.7.1.29 FAD inhibits the dihydroxyacetone kinase activity Rattus norvegicus
4.6.1.15 ATP inhibits the FMN cyclase activity Homo sapiens
4.6.1.15 ATP inhibits the FMN cyclase activity Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.29 59400
-
 x * 59400, SDS-PAGE Homo sapiens
4.6.1.15 59400
-
 x * 59400, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.29 Homo sapiens Q3LXA3
-
-
2.7.1.29 Rattus norvegicus
-
-
-
4.6.1.15 Homo sapiens Q3LXA3
-
-
4.6.1.15 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.29
-
 Rattus norvegicus
2.7.1.29
-
 Homo sapiens
4.6.1.15
-
 Rattus norvegicus
4.6.1.15
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.29 brain
-
 Homo sapiens
-
2.7.1.29 liver
-
 Rattus norvegicus
-
4.6.1.15 brain
-
 Homo sapiens
-
4.6.1.15 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.6.1.15 0.01 0.02 FMN cyclase activity, lysate supernatant of BL21 cells, pH7.5, 37°C Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.29 dihydroxyacetone + ATP
-
 Rattus norvegicus dihydroxyacetone phosphate + ADP
-
 ?
2.7.1.29 dihydroxyacetone + ATP
-
 Homo sapiens dihydroxyacetone phosphate + ADP
-
 ?
4.6.1.15 FAD
-
 Rattus norvegicus AMP + riboflavin cyclic-4',5'-phosphate
-
 ?
4.6.1.15 FAD
-
 Homo sapiens AMP + riboflavin cyclic-4',5'-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.29 ? x * 59400, SDS-PAGE Homo sapiens
4.6.1.15 ? x * 59400, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.1.29 FMN cyclase/dha kinase bifunctional enzyme Rattus norvegicus
2.7.1.29 FMN cyclase/dha kinase bifunctional enzyme Homo sapiens
4.6.1.15 FMN cyclase/dha kinase bifunctional enzyme Rattus norvegicus
4.6.1.15 FMN cyclase/dha kinase bifunctional enzyme Homo sapiens