EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.4.B1 | 5,5'-dithio-bis(2-nitrobenzoic acid) | - |
Saccharomyces cerevisiae | |
2.7.4.B1 | N-ethylmaleimide | - |
Saccharomyces cerevisiae |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.4.B1 | cytoplasm | 80% | Saccharomyces cerevisiae | 5737 | - |
2.7.4.B1 | nucleus | 20% | Saccharomyces cerevisiae | 5634 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.4.B1 | Ca2+ | 57% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Cd2+ | no activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Co2+ | 99% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Cu2+ | 11% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Fe2+ | 24% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Mg2+ | 100% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Mn2+ | 100% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Ni2+ | 84% activity at 7.5 mM | Saccharomyces cerevisiae | |
2.7.4.B1 | Zn2+ | 14% activity at 7.5 mM | Saccharomyces cerevisiae |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.4.B1 | 25000 | - |
monomer, SDS-PAGE | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.B1 | ATP + UMP | Saccharomyces cerevisiae | - |
ADP + UDP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.4.B1 | Saccharomyces cerevisiae | P15700 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.4.B1 | to homogeneity | Saccharomyces cerevisiae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.B1 | ATP + 5-iodo-dUMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + 5-iodo-dUDP | - |
? | |
2.7.4.B1 | ATP + dGMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + dGDP | - |
? | |
2.7.4.B1 | ATP + dTMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + dTDP | - |
? | |
2.7.4.B1 | ATP + dUMP | - |
Saccharomyces cerevisiae | ADP + dUDP | - |
? | |
2.7.4.B1 | ATP + GMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + GDP | - |
? | |
2.7.4.B1 | ATP + IMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + IDP | - |
? | |
2.7.4.B1 | ATP + UMP | - |
Saccharomyces cerevisiae | ADP + UDP | - |
? | |
2.7.4.B1 | ATP + UMP | pH 7.5, 7.5 mM Mg2+, 30°C | Saccharomyces cerevisiae | ADP + UDP | - |
? | |
2.7.4.B1 | ATP + XMP | reaction occurs to a lesser extent | Saccharomyces cerevisiae | ADP + XDP | - |
? | |
2.7.4.B1 | CTP + UMP | reaction rate is 10-14% of that with ATP or dATP | Saccharomyces cerevisiae | CDP + UDP | - |
? | |
2.7.4.B1 | dATP + UMP | - |
Saccharomyces cerevisiae | dADP + UDP | - |
? | |
2.7.4.B1 | dCTP + UMP | reaction rate is 30-50% of that with ATP or dATP | Saccharomyces cerevisiae | dCDP + UDP | - |
? | |
2.7.4.B1 | dGTP + UMP | reaction rate is 30-50% of that with ATP or dATP | Saccharomyces cerevisiae | dGDP + UDP | - |
? | |
2.7.4.B1 | dTTP + UMP | reaction rate is 30-50% of that with ATP or dATP | Saccharomyces cerevisiae | dTDP + UDP | - |
? | |
2.7.4.B1 | GTP + UMP | reaction rate is 30-50% of that with ATP or dATP | Saccharomyces cerevisiae | GDP + UDP | - |
? | |
2.7.4.B1 | UTP + UMP | reaction rate is 10-14% of that with ATP or dATP | Saccharomyces cerevisiae | UDP + UDP | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.4.B1 | UMP kinase | - |
Saccharomyces cerevisiae |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.4.B1 | 50 | - |
enzyme activity decreases to 55%. In the presence of 1 mM UTP enzyme activity decreases to 73%. In the presence of 10% glycerol enzyme activity decreases to 77%. In the presence of 10% polyethylene glycol enzyme activity decreases to 95%. In the presence of 10 mM DTT enzyme activity decreases to 80% | Saccharomyces cerevisiae |
2.7.4.B1 | 60 | - |
enzyme activity decreases to 3%. In the presence of 1 mM UTP enzyme activity decreases to 10%. In the presence of 10% glycerol enzyme activity decreases to 14%. In the presence of 10% polyethylene glycol enzyme activity decreases to 34%. In the presence of 10 mM DTT enzyme activity decreases to 68% | Saccharomyces cerevisiae |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.7.4.B1 | 6 | 9.5 | - |
Saccharomyces cerevisiae |