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Literature summary extracted from

  • Wopperer, J.; Cardona, S.T.; Huber, B.; Jacobi, C.A.; Valvano, M.A.; Eberl, L.
    A quorum-quenching approach to investigate the conservation of quorum-sensing-regulated functions within the Burkholderia cepacia complex (2006), Appl. Environ. Microbiol., 72, 1579-1587.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.81 gene aiiA, expression in Burkholderia cepacia, an organism of the Burkholderia complex, from a broad-host range plasmid, the expression abolishes or greatly reduces the accumulation of N-acyl-homoserine lactone molecules in the Burkholderia cepacia complex strains, phenotype, overview Bacillus sp. (in: Bacteria)

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O Bacillus sp. (in: Bacteria) N-acylhomoserine lactones, AHL, regulate protease production, swarming motility, biofilm formation, and Caenorhabditis elegans killing efficiency in most strains of the Burkholderia complex organisms, which is inhibited by Bacillus AHL lactonase acting as a quorum-quenching enzyme N-acyl-(S)-homoserine
-
 ?
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O Bacillus sp. (in: Bacteria) 240B1 N-acylhomoserine lactones, AHL, regulate protease production, swarming motility, biofilm formation, and Caenorhabditis elegans killing efficiency in most strains of the Burkholderia complex organisms, which is inhibited by Bacillus AHL lactonase acting as a quorum-quenching enzyme N-acyl-(S)-homoserine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.81 Bacillus sp. (in: Bacteria)
-
 isolated from soil, gene aiiA
-
3.1.1.81 Bacillus sp. (in: Bacteria) 240B1
-
 isolated from soil, gene aiiA
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O
-
 Bacillus sp. (in: Bacteria) N-acyl-(S)-homoserine
-
 ?
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O N-acylhomoserine lactones, AHL, regulate protease production, swarming motility, biofilm formation, and Caenorhabditis elegans killing efficiency in most strains of the Burkholderia complex organisms, which is inhibited by Bacillus AHL lactonase acting as a quorum-quenching enzyme Bacillus sp. (in: Bacteria) N-acyl-(S)-homoserine
-
 ?
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O
-
 Bacillus sp. (in: Bacteria) 240B1 N-acyl-(S)-homoserine
-
 ?
3.1.1.81 N-acyl-(S)-homoserine lactone + H2O N-acylhomoserine lactones, AHL, regulate protease production, swarming motility, biofilm formation, and Caenorhabditis elegans killing efficiency in most strains of the Burkholderia complex organisms, which is inhibited by Bacillus AHL lactonase acting as a quorum-quenching enzyme Bacillus sp. (in: Bacteria) 240B1 N-acyl-(S)-homoserine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.81 AiiA lactonase
-
 Bacillus sp. (in: Bacteria)